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Pyrimidine nucleoside analogues, for instance BVDU and BVaraU, can be degraded by pyrimidine catabolic enzymes (for example uridine phosphorylase or thymidine phosphorylase (TPase) leading to their free of charge foundation metabolites with out antiviral activity. BVDU can't be administered together with 5-flurouracil or its prodrug capecitabine si

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